Facile synthesis of hierarchical porous metal–organic framework confined ruthenium nanozyme for efficient enrichment and specific detection of perfluorooctane sulfonate in environmental water samples

Title : Facile synthesis of hierarchical porous metal–organic framework confined ruthenium nanozyme for efficient enrichment and specific detection of perfluorooctane sulfonate in environmental water samples

Abstract:

Perfluorooctane sulfonate (PFOS) is a persistent organic pollutant that poses severe risks to human health and ecosystems due to its significant bioaccumulation and environmental persistence. Therefore, developing precise, cost-effective, and field-deployable analytical methods for PFOS detection is critically needed. This work designed a nanozyme-based adsorbent (UiO-66@4F-BDC@Ru) for efficient enrichment and highly selective recognition of PFOS. Through a post-synthetic ligand modification strategy, tetrafluorobis(dichlorobenzene) ligand (4F-BDC) was grafted onto the UiO-66 framework, yielding a fluorine-enriched, hierarchically porous metal–organic framework (UiO-66@4F-BDC). Characterization via XPS and DFT calculations elucidated a synergistic adsorption mechanism governed by electrostatic attraction, coordinative binding, and F–F interactions, affording a maximum adsorption capacity of 340.83 mg/g. The adsorption process conformed to Langmuir and pseudo-second-order kinetic models, demonstrating outstanding adsorption performance. Importantly, the hierarchical pore architecture of UiO-66@4F-BDC functions as a spatially confined carrier for Ru nanoparticles successfully constructing a nanozyme adsorbent (UiO-66@4F-BDC@Ru) with highly selective adsorption and enhanced peroxidase-mimicking activity. This enabled rapid, visual, and ultrasensitive detection of PFOS with a detection limit as low as 6.8 ng/mL. The constructed colorimetric platform exhibits excellent linear dynamic range from 0.01 to 20 μg/mL (R2 = 0.9928), strong resistance to matrix interference, good regenerative performance, and practical applicability in environmental water systems (spiked recoveries of 87.6%–99.7%). This work not only provides a novel strategy for developing nanozyme materials that combine targeted enrichment with highly sensitive detection but also offers a practical solution for the removal and monitoring of persistent organic pollutants in food processing and environmental systems.

Biography:

Dr. Li is studying Food Science and Engineering at Tianjin University of Science and Technology and obtained a Master of Medicine degree in 2024. Subsequently, she joined the research team of Professor Pan Mingfei at the School of Food Science and Engineering of Tianjin University of Science and Technology to pursue a doctoral degree. Her research direction is the precise and rapid analysis and detection of trace toxic and harmful substances in Food safety. She has published more than 8 research articles in SCI journals such as Advanced Composites and Hybrid Materials, Trends in Food Science and Technology, Chemical Engineering Journal, Food Chemistry and Analytica Chimica Acta.