Title : Synthesis of an oligomer derived from biobased composite and valorization of its antibacterial activities
Abstract:
Gallic acid and its esters are chemical compounds of plant origin considered as biobased materials, which contribute significantly to the growing interest in sustainable and renewable resources. They have very good antioxidant activity, because their possibility to be free radical scavengers. These compounds can be extracted from various plants such as clove, green tea, gall nut… and especially in fruits: cherries, bananas, dates...These chemical compounds find significant applications in various industries. Iin the pharmaceutical industry due to its various therapeutic activities, such as anti-inflammatory, antimicrobial, and anticancer properties. In the cosmetic industry they are used as anti-aging agents and to address issues like hair loss or skin damage. Ans also, in the food industry, they act as natural preservatives, food additives and flavor enhancers.
In this work, we propose a green synthesis of a tetra ester “oligomer” derived from gallic acid, aiming for an environmentally friendly approach. The structure of this product is confirmed using infrared spectroscopy, 1H NMR and 13C NMR spectroscopy, ensuring its chemical identity. Following the synthesis, its antibacterial activities were evaluated using the conventional disk diffusion method. This study utilized both Gram-negative and Gram-positive bacterial pathogens to assess the compound’s effectiveness.
The results of this investigation underscore the multifunctional potential of gallic acid esters. Their exceptional combination of antioxidant, antimicrobial, and industrially relevant properties makes them promising candidates for further exploration and development. These findings pave the way for their utilization in designing innovative products for pharmaceutical, cosmetic, and food-related applications, fostering advancements in sustainable and functional biobased materials
