Title : Eliminating implant failure in humans with nano chemistry: 30,000 cases and counting
Abstract:
Nanomedicine is the use of nanomaterials to improve disease prevention, detection, and treatment which has resulted in hundreds of FDA approved medical products. While nanomedicine has been around for several decades, new technological advances are pushing its boundaries. For example, this presentation will present an over 25 year journey of commercializing nano orthopedic implants now in over 30,000 patients to date showing no signs of failure. Current orthopedic implants face a failure rate of 5 – 10% and sometimes as high as 60% for bone cancer patients. Further, Artificial Intelligence (AI) has revolutionized numerous industries to date. However, its use in nanomedicine has remained few and far between. One area that AI has significantly improved nanomedicine is through implantable sensors and neurological applications. This talk will present research in which implantable sensors, using AI, can learn from patient’s response to implants and predict future outcomes. Such implantable sensors not only incorporate AI, but also communicate to a handheld device, and can reverse AI predicted adverse events. Examples will be given in which AI implantable sensors have been used in neurology to inhibit implant infection and promote prolonged neural function. Moreover, in vitro and in vivo experiments will be provided that demonstrate how nanotechnology can be incorporated into neurology to help human health.
